Table 1.
Demographic and clinical characteristics (combined and stratified by neurocognitive impairment)
| Characteristics | All subjects | NC impaired | NC unimpaired | |
|---|---|---|---|---|
| ( n = 107) | ( n = 58) | ( n = 49) | P value | |
| Age, years - mean ± SD | 43.7 ± 8.7 | 45.3 ± 9.3 | 41.8 ± 7.6 | 0.033 |
| Gender, male - N (%) | 93 (86.9%) | 52 (89.7%) | 42 (85.7%) | 0.406 |
| Race | ||||
| White - N (%) | 59 (55.1%) | 31 (53.5%) | 28 (57.1%) | 0.962 |
| Black | 34 (31.8%) | 18 (31.0%) | 16 (32.7%) | |
| Other | 14 (13.1%) | 9 (15.5%) | 5 (10.2%) | |
| AIDS - N (%) | 68 (63.6%) | 38 (65.5%) | 30 (61.2%) | 0.554 |
| ART use - N (%) | 84 (78.5%) | 45 (77.6%) | 39 (79.6%) | 0.956 |
| Plasma HIV VL undetectable - N (%) | 53 (49.5%) | 29 (50.0%) | 24 (50.0%) | 0.838 |
| CSF HIV VL undetectable - N (%) | 79 (73.8%) | 44 (75.9%) | 36 (73.5%) | 0.910 |
| Current CD4+ count (<200 cells/μL) - N (%) | 22 (20.8%) | 9 (15.5%) | 13 (26.5%) | 0.160 |
| Current CD4+ count - median (IQR) | 405 (216 to 582) | 435 (260 to 589) | 360 (175 to 531) | 0.247 |
| Albumin (<5 g/dL) | 72 (67.9%) | 37 (64.9%) | 35 (71.4%) | 0.474 |
| Alcohol dependence - N (%) | 25 (23.2%) | 12 (20.7%) | 13 (26.5%) | 0.514 |
| HGB (mean ± SD) | 14.1 ± 1.5 | 14.1 ± 1.6 | 14.1 ± 1.4 | 0.882 |
| AST - median (IQR) | 30 (23 to 37) | 31 (24 to 39) | 30 (22 to 36) | 0.673 |
| ALT - median (IQR) | 33 (22 to 43) | 36 (23 to 43) | 30 (22 to 40) | 0.298 |
| Body mass index (BMI) | 0.290 | |||
| BMI ≤ 25 | 45 (42.1%) | 24 (41.4%) | 21 (42.9%) | |
| 25 < BMI < 30 | 45 (42.1%) | 22 (37.9%) | 23 (46.9%) | |
| BMI ≥ 30 | 17 (15.8%) | 12 (20.7%) | 5 (10.2%) |