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. 2015 Apr 18;16(1):320. doi: 10.1186/s12864-015-1517-1

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© Guo et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Structural organization of two Illumina-sequenced genomes of Cryptosporidium hominis comparing to eight chromosomes (numbered and separated by vertical red lines) of published Cryptosporidium parvum genome. The color blocks (known as Locally Collinear Blocks) are conserved segments of sequences internally free from genome rearrangements, whereas the inverted white peaks within each block are sequence divergence between the reference C. parvum (IOWA) genome and C. hominis genome under analysis. A. Coverage of two C. hominis genomes showing possible sequence rearrangements in chromosomes 2, 4, 5 and 6. Assembled contigs are bordered by vertical red lines. For specimens 30976, only Cryptosporidium contigs were used in mapping. B. Possible sequence rearrangements at the 5′ end of chromosome 2. C. Possible sequence rearrangements in chromosomes 4 and 5.