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. 2015 Apr 9;2015:929131. doi: 10.1155/2015/929131

Table 2.

In vivo effect of A. mellifera (AM) crude ethanolic extract on CCl4-induced lipid profile changes.

Treatment group Dose mg/kg TC (mg/dL) TG (mg/dL) HDL-C (mg/dL) LDL-C (mg/dL) VLDL-C (mg/dL)
Normal 88.09 ± 6.5 78.26 ± 4.09 50.82 ± 1.25 72.24 ± 6.34 15.56 ± 0.65
CCl4 1.25 mL/kg 212.69 ± 7.84∗∗∗a 184.05 ± 8.09∗∗∗a 22.14 ± 0.56∗∗∗a 175.80 ± 8.42∗∗∗a 36.81 ± 1.69∗∗∗a
AM + CCl4 250 169.04 ± 11.25∗∗∗b 168.59 ± 9.17b 28.26 ± 1.25∗∗b 135.22 ± 10.18∗b 33.71 ± 1.83b
AM + CCl4 500 136.50 ± 4.70∗∗∗b 117.37 ± 7.01∗∗∗b 36.76 ± 1.02∗∗∗b 112.89 ± 4.02∗∗∗b 23.47 ± 1.40∗∗∗b
Silymarin + CCl4 10 124.60 ± 5.94∗∗∗b 98.55 ± 5.60∗∗∗b 35.34 ± 1.81∗∗∗b 104.74 ± 5.93∗∗∗b 19.71 ± 1.12∗∗∗b

All values represent mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001; ANOVA, followed by Dunnett's multiple comparison test. aAs compared with normal group. bAs compared with CCl4 only group.