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. 2015 Apr 22;5:19. doi: 10.1186/s13578-015-0010-5

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© Visagie et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Caspase 7 activation by EMBS. Caspase 7 activity of vehicle-treated MCF-7 (A), MDA-MB-231 (B) MCF-12A cells (C), EMBS-treated MCF-7 (D), MDA-MB-231 (E), MCF-12 A cells (F) and actinomycin D-treated MCF-7 (G), MDA-MB-231 (H) and MCF-12A (I). Data showed an increase in the number of cells with increased caspase 7 activity after exposure to EMBS when compared to cells vehicle-treated cells. Actinomycin D-treated cells were used as a positive control for apoptosis and caspase activation and displayed significant elevated caspase 7 activity when compared to vehicle-treated cells.