Table 2.

Allelic Patterns Seen in Cells Isolated from Blood (Populations CD45⁻, CD235a⁻, and CD45⁻, CD235a⁺) of Patients with One Visit: Distribution of Allelic Patterns in Those with Loss of Heterozygosity in Both CD45⁻, CD235a⁻ and CD45⁻, CD235a⁺ Populations

Allelic Pattern	No. (%) of Patients	Mean Age ± SD (yr)	TSC (n)
CD45−, CD235a− = CD45−, CD235a+	23 (74.2)	47.4 ± 11.8	4
CD45−, CD235a− ≠ CD45−, CD235a+	8 (25.8)	47.7 ± 8.9	2

Definition of abbreviations: LOH = loss of heterozygosity; ROH = retention of heterozygosity; TSC = tuberous sclerosis complex.

TSC column shows the number of patients in that category who have tuberous sclerosis. Allelic pattern refers to the combination of ROH and LOH seen across the five markers tested (D16S521, D16S3024, D16S3395, Kg8, and D16S291). CD45⁻, CD235a⁻ = CD45⁻, CD235a⁺: the pattern is the same in cells from populations CD45⁻, CD235a⁻ and CD45⁻, CD235a⁺ (see L139 or L186 in Figure E1 for example); CD45⁻, CD235a⁻ ≠ CD45⁻, CD235a⁺: the pattern is different in cells from population CD45⁻, CD235a⁻ versus CD45⁻, CD235a⁺ (see L47 or L80 in Figure E1 for example).