Table 2.
Stereoscopic SGN counts of three animals per treatment group and 30 measures per animal for each of upper basal. Middle and upper middle turns within the cochleae. Statistically significant ANOVA SGN density differences were observed between 0 mg/kg and 1.2 mg/kg minocycline and between 0 mg/kg and 1.5 mg/kg minocycline (P < 0.05).
| Turn within cochlea | Minocycline concentration | ||
|---|---|---|---|
| 0 mg/kg | 1.2 mg/kg | 1.5 mg/kg | |
| Spiral ganglion cell density in Rosenthal's canal (cells/mm2) | |||
| Upper basal | 712 ± 241 | 1273 ± 374 | 867 ± 193 |
| Middle | 787 ± 306 | 1201 ± 285 | 951 ± 315 |
| Upper middle | 780 ± 263 | 1129 ± 188 | 920 ± 321 |
| Average of all turns | 759 ± 263 | 1203 ± 315 | 929 ± 276 |