Table 3.
KEGG pathway enrichment analysis of Epinephelus coioides larvae
| List | KEGG pathway | NGS with pathway annotation (1504) | All genes with pathway annotation (32664) | P-value | Q-value | Pathway ID |
|---|---|---|---|---|---|---|
| Metabolism | ||||||
| Carbohydrate metabolism | ||||||
| 12 | Glycolysis/Gluconeogenesis | 25 (1.66%) | 173 (0.53%) | 4.10E-07 | 7.42E-06 | ko00010 |
| 18 | Starch and sucrose metabolism | 21 (1.4%) | 167 (0.51%) | 2.98E-05 | 3.59E-04 | ko00500 |
| Cellular processes | ||||||
| Cell communication | ||||||
| 9 | Tight junction | 112 (7.45%) | 1224 (3.75%) | 3.60E-12 | 8.68E-11 | ko04530 |
| Transport and catabolism | ||||||
| 15 | Phagosome | 55 (3.66%) | 651 (1.99%) | 1.27E-05 | 1.84E-04 | ko04145 |
| Cell motility | ||||||
| 16 | Regulation of actin cytoskeleton | 98 (6.52%) | 1387 (4.25%) | 1.81E-05 | 2.45E-04 | ko04810 |
| Organismal systems | ||||||
| Circulatory system | ||||||
| 1 | Cardiac muscle contraction | 108 (7.18%) | 742 (2.27%) | 1.81E-26 | 3.94E-24 | ko04260 |
| 11 | Vascular smooth muscle contraction | 88 (5.85%) | 988 (3.02%) | 2.97E-09 | 5.86E-08 | ko04270 |
| Digestive system | ||||||
| 2 | Protein digestion and absorption | 91 (6.05%) | 575 (1.76%) | 4.50E-25 | 4.88E-23 | ko04974 |
| 10 | Pancreatic secretion | 70 (4.65%) | 618 (1.89%) | 4.61E-12 | 1.00E-10 | ko04972 |
| Immune system | ||||||
| 5 | Complement and coagulation cascades | 60 (3.99%) | 341 (1.04%) | 3.13E-19 | 1.36E-17 | ko04610 |
| 17 | Antigen processing and presentation | 20 (1.33%) | 152 (0.47%) | 2.36E-05 | 3.01E-04 | ko04612 |
| Diseases | ||||||
| Infectious diseases: bacterial | ||||||
| 6 | Staphylococcus aureus infection | 44 (2.93%) | 206 (0.63%) | 1.00E-17 | 3.62E-16 | ko05150 |