Table 2.
Summary of transduced and non-transduced DLI: peripheral blood of all patients was screened routinely for the presence of transduced cells with FACS and PCR.
| UPN | Gebdat | Age_HSCT (1st and 2nd) | DLI | DLI-days-post-HSCT | Cells/kg BW |
|---|---|---|---|---|---|
| 914 | 06.07.1957 | 45 | DLI(HSV-TK) | 71 | 1 × 10E7 |
| 914 | 06.07.1957 | 45 | DLI chimerism | 178 | 1 × 10E7 |
| 91A | 06.07.1957 | 45 | DLI chimerism | 249 | 1 × 10E7 |
| 91A | 06.07.1957 | 45 | DLI chimerism | 329 | 3 × 10E7 |
| 91A | 06.07.1957 | 45 | DLI chimerism | 406 | 5,3 × 10E7 |
| 919 | 03.02.1967 | 35 | DLI(HSV-TK) | 87 | 4 × 10E6 |
| 1021 | 02.12.1963 | 39 | DLI(HSV-TK) | 113 | 1,3 x10E7 |
| 1021 | 02.12.1963 | 39 | DLIrelapse | 2535 | 1,8 × 10E7 |
| 1021 | 02.12.1963 | 39 | DLIrelapse | 2564 | 1,12 × 10E8 |
| 1021 | 02.12.1963 | 39 | DLIrelapse | 2592 | 2 × 10E8 |
| 1040 | 28.12.1952 | 50 | Stemcell boost | 191 | 6 × 10E6 CD34+ |
| 1040 | 28.12.1952 | 50 | DLI(HSV-TK) | 330 | 1 × 10E7 |
| 1040 | 28.12.1952 | 53 | DLIprophylaxis | 268 | 1,03 × 10E6 |
| 1040 | 28.12.1952 | 53 | DLIprophylaxis | 304 | 5 × 10E6 |
| 1040 | 28.12.1952 | 53 | DLIprophylaxis | 339 | 1 × 10E7 |
| 1040 | 28.12.1952 | 53 | DLIrelapse | 535 | 5 × 10E7 |
| 1040 | 28.12.1952 | 53 | DLIrelapse | 563 | 1 × 10E8 |
| 1040 | 28.12.1952 | 53 | DLIrelapse | 612 | 1,23 × 10E8 |
| 1048 | 23.01.1965 | 38 | DLI(HSV-TK) | 100 | 1,5 × 10E7 |
| 1108 | 18.02.1953 | 51 | DLI(HSV-TK) | 126 | 4 × 10E6 |
| 1159 | 23.12.1968 | 35 | DLI(HSV-TK) | 136 | 7,5 x10E6 |
| 1190 | 10.03.1966 | 38 | DLI(HSV-TK) | 129 | 1 × 10E7 |
| 1208 | 06.12.1953 | 51 | DLI(HSV-TK) | 73 | 1,3 × 10E7 |
| 1208 | 06.12.1953 | 51 | DLIrelapse | 519 | 1,8 × 10E7 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 377 | 5,38 × 10E4 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 405 | 1,3 × 10E5 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 433 | 4,7 × 10E5 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 461 | 1,27 × 10E6 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 488 | 5 × 10E6 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 517 | 1 × 10E7 |
| 1269 | 10.04.1987 | 18 | DLIrelapse | 545 | 5,03 × 10E7 |
| 1438 | 13.10.1972 | 34 | No | na | |
| 1550 | 25.04.1982 | 25 | No | ||
| 1505 | 16.12.1983 | 23 | DLI(HSV-TK) | 48 | 1 × 10E6 |
| 1505 | 16.12.1983 | 23 | DLI(HSV-TK) therapy | 222 | 1 × 10E6 |
| 1551 | 18.08.1975 | 32 | DLI(HSV-TK) | 42 | 1 × 10E6 |
The number of transduced (first DLI) and non-transdcued DLI (for loss of chimerism or relapse) are shown as number of transduced cells (CD3+ cells) or as number of leukocytes transfused per kg body weight.