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Activation of PARP during heat shock-induced gemcitabine sensitization. Immunoblotting displaying dose-dependent cleavage of PARP in PL5 cells exclusively upon combined treatment with heat shock at 41.8°C for 90 min., followed by gemcitabine at 25 or 50 nM for 24 hrs, but not upon either treatment alone. ß-ACTIN served as loading control.
