Fig 7.

Influence of HeLa-treated cells conditioned media on HUVEC cells ability to form capillary tubes. HeLa cells were treated for 48 hrs with siRNA, the media were collected and used to culture HUVEC cells in 4-well slides pre-coated with fibrin gels. When cultured in negative control siRNA conditioned media, the HUVEC cells showed no ability to form capillary tubes neither after 5 hrs (A) or 24 hrs (C) of culturing. However, the cells show clear aggregation tendencies, which seems to be abolished when the cells were cultured in PDGFBB siRNA conditioned media (B and D).