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. 2015 Apr 23;6:52. doi: 10.3389/fendo.2015.00052

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Copyright © 2015 Galea, Hannuna, Meakin, Delisser, Lanyon and Price.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of response of the mouse tibia to neurectomy-induced disuse at each site along the bone’s length. Site specificity analysis of (A) Cs.Th, (B) Ct.Ar, (C) Tt.Ar, (D) Ma.Ar, (E) absolute anterior–posterior, and (F) medial–lateral centroid deviation calculated from control left tibiae and disused right tibiae from the same mice, n = 6. Dots/bars above the graphs indicate sites of significant difference, p < 0.05 following Bonferroni correction. Interactions are the site by neurectomy interactions calculated by mixed models; ns not significant, ***p < 0.001.