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. 2015 Jan 26;9:13. doi: 10.1186/1752-1947-9-13

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© Carlomagno et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Hematoxylin and eosin infiltration of gastric wall (a) by cells organized in a solid pattern with foci of necrosis (b) by neoplastic cells with pleomorphic nuclei and high nucleocytoplasmic ratio, with a trabecular and organoid pattern; (c) by tumor cells with vesicular nuclei, amphophilic cytoplasm, in a solid pattern of growth with central necrosis. (d) At immunohistochemistry neoplastic cells with high CD56 membrane positivity suspicious for neuroendocrine differentiation.