Figure 3.
CLDN4 and FUT4 methylation probe allocation in Illumina HumanMethylation450 array (450 array). CLDN4 and FUT4 DNA methylation probes in 450 array were targeting multiple CpG sites across whole gene regions. The CpG sites with significantly increased CpG methylation were located in the enhancer region (or first Exon). CLDN4 (chr7: 73245752); FUT4 (chr11: 94278324-chr11: 94278603) *P < 0.001; **P < 0.01.