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. Author manuscript; available in PMC: 2015 Apr 23.
Published in final edited form as: J Microencapsul. 2014 Apr 3;31(6):542–550. doi: 10.3109/02652048.2014.885606

Table 3.

Effect of pH on Fab:DS HIP NPs size and zeta potential. (a) Particle size of Fab:DS HIP NPs with respect to pH and (b) Zeta potential of Fab:DS HIP NPs with respect to pH.

No Method of preparation Drug pH Particle size (nm)
(a) Particle size of Fab:DS HIP NPs with respect to pH
1 Nanoprecipitation method Fab:DS HIP 7.45 222.10 ±5.54
6 217.55 ±0.97
5 216.05 ± 1.77
4 284.70 ±9.41
2 S/O/W method Fab:DS HIP 7.45 171.90 ±3.87
6 174.40 ±2.77
5 175.47 ±3.23
4 173.90 ±2.17
(b) Zeta potential of Fab:DS HIP NPs with respect to pH. Zeta potential (mV)

1 Nanoprecipitation method Fab:DS HIP 6 −10.25 ± 0.07
4 −3.63 ±0.09
2 S/O/W method Fab:DS HIP 6 −5.47 ± 1.68
4 −4.80 ±0.66

Note: Values are represented as mean ± SD (n = 3).