TABLE 1.
Summary of whole (center + perimeter) open field activity measures: 36 DPI
| Output Measure: Center + Perimeter | VEH (0.5% Methylcellulose; n = 12) | VPA (200 mg/kg b.i.d.; n = 19) | CBZ (20 m/kg b.i.d.; n = 17) | Overall Analysis of Variance P Value |
|---|---|---|---|---|
| Total distance (cm) | 1265.1 ± 161.5 | 1361.0 ± 231.7 | 1600.8 ± 233.1 | 0.56 |
| Horizontal activity counts | 1889.5 ± 216.6 | 1736.0 ± 222.4 | 2124.9 ± 235.8* | 0.046 |
| Vertical activity counts | 254.0 ± 49.3 | 180.5 ± 30.1 | 209.3 ± 30.6 | 0.35 |
| Rest time (s) | 216 ± 15.3 | 229.9 ± 20.3 | 195.0 ± 17.1 | 0.37 |
| Stereotypy time (s) | 13.9 ± 1.1 | 12.5 ± 0.9 | 14.9 ± 1.1 | 0.22 |
*
Significantly different from VEH by one-way analysis of variance and Tukey’s post hoc test.