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Reversal of inhibition by exogenous guanosine. Vero cells were infected with DENV-2 and treated with 100 μM 3b (A) or 200 μM RIB (B) in the presence or absence of different guanosine concentrations. Other set of cultures were infected with DENV-2 and incubated with different concentrations of guanosine alone (C). After 48 h, extracellular virus yields were determined by plaque formation. Each value is the mean of triplicate assays ± standard deviation. (***), P ≤ 0.001.
