Table 1.
Baseline demographics and disease characteristics
| Baseline characteristic | Treatment group (n = 90) | Control group (n = 90) | P value |
|---|---|---|---|
| Age, years (mean ± SD) | 68.8 ± 7.1 | 69.0 ± 7.1 | 0.9349* |
| Female, n (%) | 54 (60.0) | 59 (65.6) | 0.4407** |
| Patient with concomitant systemic diseases, n (%) | 25 (27.8) | 26 (28.9) | 0.8686** |
| TBUT, s (mean ± SD) | 7.7 ± 4.8 | 7.2 ± 4.1 | 0.7583* |
| Schirmer test, mm (mean ± SD) | 12.6 ± 6.9 | 12.9 ± 6.9 | 0.6800* |
| Percentage of patients with dry eye, n (%) | |||
| TBUT ≤5 s + symptom score ≥3 | 34 (37.8) | 32 (35.6) | |
| Schirmer test ≤3 mm + symptom score ≥3 | 2 (2.2) | 4 (4.4) | |
| Total patients with dry eye | 35 (38.9) | 33 (36.7) | 0.7585** |
SD, standard deviation; TBUT, tear film breakup time.
*Wilcoxon rank sum test.
**Chi-square test.