Table 2.
Genotype and Allele frequencies of VEGF variants in controls , DM and DN groups
| Genotypes | OR (95% C.I.) for DD genotype | ||||
|---|---|---|---|---|---|
| II | ID | DD | P value | ||
| Controls (40) | 10 (25) | 19 (47.5) | 11 (27.5) | 0.02 | |
| DM (40) | 9 (22.5) | 22 (55) | 9 (22.5)* | 4.2 (1.28-4.63)a | |
| DN (40) | 7 (17.5) | 11 (27.5) | 22 (55)** | ||
| Alleles | O.R. (95% C.I.) for for D allele | ||||
| I | D | P value | |||
| Controls (40) | 39 (48.75) | 41 (51.25) | 0.02 | ||
| DM (40) | 40 (50) | 40 (50)@ | 2.2 (1.15-4.19)b | ||
| DN (40) | 25 (31.25) | 55 (68.75)# | |||
*p value 0.79 (statistically insignificant) Vs controls.
**p value 0.02 and 0.009 vs controls and DM group respectively.
aDN group Vs DM group against combined frequency of II and ID genotype.
@p value 0.5 (statistically insignificant) Vs controls.
#p value 0.01 and 0.02 vs controls and DM group respectively.
bDN group Vs DM group against frequency of I allele.