Table 5. The DE genes associated with apoptosis in each infection group.
| Group | Description | Gene symbol | Gene ID | Fold change |
|---|---|---|---|---|
| H1N1 | C1D nuclear receptor corepressor | C1D | 100515656 | 4.23 |
| cytoplasmic FMR1 interacting protein 2 | CYFIP2 | 100523290 | 1.93 | |
| Rep: baculoviral IAP repeat-containing protein 2 | BIRC2 | 100622859 | -1.85 | |
| RING1 and YY1 binding protein | RYBP | 100526249 | -1.71 | |
| lymphotoxin beta (TNF superfamily, member 3) | LTB | 100155581 | 1.63 | |
| lipopolysaccharide-induced TNF factor | LITAF | 100518302 | -1.62 | |
| tumor necrosis factor receptor superfamily, member 1B | TNFRSF1B | 100037306 | 1.58 | |
| sulfatase 1 | SULF1 | 100152427 | -1.53 | |
| SS2 | cellular FLICE-like inhibitory protein | C-FLIP | 414381 | 2.24 |
| tumor necrosis factor receptor superfamily, member 8 | TNFRSF8 | 574055 | 2.08 | |
| death-associated protein kinase 2 | DAPK2 | 100155578 | -1.94 | |
| Rep: Mdm4, transformed 3T3 cell double minute 4, p53 binding protein isoform 1 | MDM4 | 100512731 | -1.94 | |
| programmed cell death 4 (neoplastic transformation inhibitor) | PDCD4 | 100157112 | -1.76 | |
| tumor necrosis factor receptor superfamily, member 1B | TNFRSF1B | 100037306 | 1.64 | |
| H1N1-SS2 | caspase 10, apoptosis-related cysteine peptidase | CASP10 | 100154896 | 1.55 |
| granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | GZMB | 100233184 | 4.29 | |
| Fas ligand (TNF superfamily, member 6) | FASLG | 396726 | 3.33 | |
| BCL2-like 11 (apoptosis facilitator) | BCL2L11 | 396632 | 2.40 | |
| caspase 4, apoptosis-related cysteine peptidase | CASP4 | 100522887 | 2.36 | |
| tumor necrosis factor receptor superfamily, member 10a | TNFRSF10A | 100134832 | 2.11 | |
| cell death-inducing DFFA-like effector c | CIDEC | 100127161 | 1.96 | |
| BCL2-like 14 (apoptosis facilitator) | BCL2L14 | 100514901 | 1.81 | |
| caspase 2, apoptosis-related cysteine peptidase | CASP2 | 100521118 | 1.81 | |
| adenomatous polyposis coli | APC | 100517932 | -1.81 | |
| tumor necrosis factor receptor superfamily, member 8 | TNFRSF8 | 574055 | 1.75 | |
| Rep: baculoviral IAP repeat-containing protein 2 | BIRC2 | 100622859 | 1.75 | |
| Rep: HECT, UBA and WWE domain containing 1 | HUWE1 | 100517442 | 1.65 | |
| PREDICTED: Sus scrofa tumor necrosis factor alpha-induced protein 8-like | TNFAIP8 | 100524014 | 1.64 | |
| tumor necrosis factor receptor superfamily, member 11b | TNFRSF11B | 100049688 | -1.63 | |
| DNA-damage-inducible transcript 3 | DDIT3 | 100240743 | 1.62 | |
| tumor necrosis factor receptor superfamily, member 1B | TNFRSF1B | 100037306 | 1.54 | |
| caspase 3, apoptosis-related cysteine peptidase | CASP3 | 397244 | 1.51 |
The DE genes associated with apoptosis were based on GO term and manual annotation. Manual annotations were listed in italics. Many genes with multiple functions were only listed in one category.