TABLE 2.

Anti-xenogeneic and anti-allogeneic lgG antibody^a, and anti-xenogeneic and anti-allogeneic cytotoxicity^b

Baboon ID	Pre-MFI Anti-Xeno	Pre-MFI Anti-Allo	Anti-Xeno Post 1°	Anti-Allo Post 1°	Anti-Xeno Post 2°	Anti- Alio Post 2°	Precytotox Anti-Xeno	Precytotox Anti-Allo	Anti-Xeno Post 1°	Anti-Allo Post 1°	Anti-Xeno Post 2°	Anti-Allo Post 2°
Group 1: primary alio; secondary xeno
8321	1	1	16	1	225	55	1:2	1:2	1:512	1:512	>1:1024	1:512
8322	183	1	202	1	1,275	22	1:8	1:2	1:16	1:128	1:256	1:128
83411	149	4	158	7	1,252	40	1:32	1:2	1:64	>1:1024	>1:1024	1:512
83511	29	4	20	69	1,114	28	1:64	1:2	1:64	1:64	>1:1024	1:512
Group 2: primary xeno; secondary alio
8297	3	4	17	6	10	4	1:2	ND	1:64	ND	1:16	ND
81011	305	15	1,286	11	1,433	14	1:16	1:2	1:512	1:2	1:256	1:32
83811	9	4	426	5	552	5	1:32	1:2	>1:1024	1:2	1:256	1:1024
83911	62	8	791	9	1,526	57	1:64	1:2	>1:1024	1:16	>1:1024	1:1024

^aAnti-xenogeneic and allogeneic antibody binding data is shown as the mode of fluorescence intensity (MFI) of IgG antibody binding.

^bThe cytotoxicity titer is defined as the dilution after which percentage cytotoxicity falls below 50% of maximum. ND designates that the assay was not done. B297* had an abnormal antibody response, in comparison to other animals, producing IgM (MFI=169) but low IgG (MFI=14).