Table 1. Clinical characteristics of insulin resistant and non-insulin resistant obese and control children/adolescents.
| IR + (n = 37) | IR- (n = 35) | Controls (n = 34) | |
|---|---|---|---|
| Sex (M/F) | 17/20 | 15/20 | 17/17 |
| Age (yr) | 12.9±2.1 | 12.7±2.1 | 12.6±2.0 |
| Weight (Kg) | 86±21* | 85±21* | 47±7 |
| Body mass index (Kg/m2) | 33±10* | 33±9* | 24±1 |
| Body mass index Z-score | 2.7±0.7* | 2.6±0.7* | 0.7±0.6 |
| Body surface area (m2) | 1.5±0.7 | 1.4±0.7 | 1.2±0.5 |
| Fasting glucose (mg/dl) | 87.1±8.4* † | 74.4±6.5 | 75.7±4.4 |
| Fasting insulin (μU/ml) | 17.1±6.3* † | 7.7±4.4 | 6.7±3.0 |
| HOMA-IR | 3.7±0.7* † | 1.4±0.7 | 1.3±0.4 |
| hsCRP (mg/dl) | 0.67±0.14* † | 0.55±0.11* | 0.40±0.14 |
| Total cholesterol (mg/dl) | 144±17 | 145±16 | 143±16 |
| HDL-cholesterol (mg/dl) | 41±7* | 43±7* | 54±6 |
| LDL-cholesterol (mg/dl) | 82±16* | 81±17* | 70±15 |
| Triglycerides (mg/dl) | 107±44 | 105±43 | 97±25 |
| Systolic blood pressure (mm Hg) | 120±10* | 121±7* | 107±6 |
| Diastolic blood pressure (mm Hg) | 66±7 | 67±7 | 66±6 |
| Heart rate (beats/min) | 71±10 | 70±10 | 69±10 |
| LFRR (ms2) | 767±94* † | 651±105 | 645±98 |
| LFRR (nu) | 49±4* † | 43±7 | 42±7 |
| HFRR (ms2) | 420±111* † | 551±114* | 690±110 |
| HFRR (nu) | 30±7* † | 37±7* | 44±5 |
| LFRR/HFRR | 2.1±0.7* † | 1.2±0.4* | 1.0±0.1 |
| LFSBP (mm Hg2) | 3.5±0.7* | 3.5±0.6* | 2.4±0.6 |
| α Index (ms/mm Hg) | 15.0±0.9* | 14.4±1.1* | 17.6±1.1 |
Data represent mean±SD;
*, p<0.05 vs controls;
†, p<0.05 vs IR-
IR+, insulin resistant obese subjects; IR-, non-insulin resistant obese subjects; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high sensitivity C-reactive protein; LFRR, low frequency power of R-R variability; nu, normalized units; HFRR, high frequency power of R-R variability; LFSBP, low frequency power of systolic blood pressure variability.