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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Curr Opin Anaesthesiol. 2015 Apr;28(2):191–200. doi: 10.1097/ACO.0000000000000165

Table 4.

Fibrinogen Depletion Studies

Hagemo et al. [27] Scandinavian journal of trauma, resuscitation, and emergency medicine. Jul 17 2013; 21(1): 56. Pig Model Single Center Early increase in fibrinogen attenuates hypocoagulable state in trauma.
Rourke et al. [26] Journal of thrombosis and hemostasis: JTH. Jul 2012; 10(7): 1342-1351. Prospective Cohort, 517 patients Single Center Low admission fibrinogen level was independently associated with injury severity score. Fibrinogen level was an independent predictor of mortality at 24 h and 28 days.
Schlimp et al. [28] Critical care. Jul 12 2013; 17(4): R137. Retrospective, 675 patients Single Center Fibrinogen upon admission correlated strongly with Hb, BE and ISS.