Table 1. Demographic characteristics and serological markers (sFLT1, PGF and ADMA) in the preeclampsia and control groups.
| Preeclampsia (n = 44) | Control (n = 100) | P-value | |
|---|---|---|---|
| Maternal age (years) | 28.61±2.81 | 29.26±2.36 | 0.071 |
| Gestational age (days) | 106.34±5.13 | 105.49±6.06 | 0.16 |
| Primiparous | 88.60% | 79.00% | 0.239 |
| First trimester Maternal BMI (kg/m2) | 21.74±2.10 | 20.57±2.88 | 0.002 |
| First trimester Maternal systolic pressure (mmHg) | 113.05±12.31 | 113.14±12.00 | 0.966 |
| First trimester Maternal diastolic pressure (mmHg) | 64.64±8.22 | 63.94±7.07 | 0.606 |
| First trimester sFLT1 (ng/ml) | 0.321±0.023 | 0.308±0.019 | 0.001 |
| First trimester PGF (pg/ml) | 115.72±32.55 | 217.30±74.48 | <0.001 |
| First trimester ADMA (μM) | 0.86±0.16 | 0.68±0.20 | <0.001 |
| Second trimester uterine artery PI | 1.19±0.20 | 0.88±0.33 | <0.001 |
| Maternal systolic pressure (mmHg)* | 152.53±7.20 | 127.00±9.3 | <0.01 |
| Maternal diastolic pressure (mmHg)* | 96.53±3.82 | 80.20±5.3 | <0.01 |
| Proteinuria (g/L) | 2.0±1.5 | 0 | <0.001 |
| Delivery age (weeks) | 36.05±2.15 | 38.33±1.57 | <0.01 |
| Birth weight (g) | 2911.09 ±328.17 | 3136.85±430.90 | <0.001 |
BMI: body mass index; PGF: placental growth factor; sFLT1: soluble fms-like tyrosine kinase 1; ADMA: asymmetric dimethylarginine; PI: pulsatility index;
*: blood pressure at diagnosis in Preeclampsia group and before delivery in control group