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. 2015 Apr 23;10(4):e0124684. doi: 10.1371/journal.pone.0124684

Table 1. Demographic characteristics and serological markers (sFLT1, PGF and ADMA) in the preeclampsia and control groups.

Preeclampsia (n = 44) Control (n = 100) P-value
Maternal age (years) 28.61±2.81 29.26±2.36 0.071
Gestational age (days) 106.34±5.13 105.49±6.06 0.16
Primiparous 88.60% 79.00% 0.239
First trimester Maternal BMI (kg/m2) 21.74±2.10 20.57±2.88 0.002
First trimester Maternal systolic pressure (mmHg) 113.05±12.31 113.14±12.00 0.966
First trimester Maternal diastolic pressure (mmHg) 64.64±8.22 63.94±7.07 0.606
First trimester sFLT1 (ng/ml) 0.321±0.023 0.308±0.019 0.001
First trimester PGF (pg/ml) 115.72±32.55 217.30±74.48 <0.001
First trimester ADMA (μM) 0.86±0.16 0.68±0.20 <0.001
Second trimester uterine artery PI 1.19±0.20 0.88±0.33 <0.001
Maternal systolic pressure (mmHg)* 152.53±7.20 127.00±9.3 <0.01
Maternal diastolic pressure (mmHg)* 96.53±3.82 80.20±5.3 <0.01
Proteinuria (g/L) 2.0±1.5 0 <0.001
Delivery age (weeks) 36.05±2.15 38.33±1.57 <0.01
Birth weight (g) 2911.09 ±328.17 3136.85±430.90 <0.001

BMI: body mass index; PGF: placental growth factor; sFLT1: soluble fms-like tyrosine kinase 1; ADMA: asymmetric dimethylarginine; PI: pulsatility index;

*: blood pressure at diagnosis in Preeclampsia group and before delivery in control group