Table 4.
Diagnostic performance of specific aPL tests in the study cohort
| Test | % (95% CI) | Odds ratio (95% CI) | ||
|---|---|---|---|---|
| Sensitivity | Specificity | Area under curve | ||
| LAC | 81·8 (48·2–97·7) | 97·9 (92·5–99·7) | 0·898 (0·778–1·0) | 204·8 (25·7–1632·7) |
| aCL IgG | 27·3 (6·02–61·0) | 97·9 (92·5–99·7) | 0·626 (0·487–0·764) | 17·1 (2·5–117·5) |
| aCL IgM | 0·0 (0·0–32·1) | 96·8 (90·2–99·2) | 0·595 (0·417–0·773) | 1·1 (0·1–23·2)* |
| aβ2GPI IgG | 27·3 (6·02–61·0) | 98·9 (94·2–100·0) | 0·679 (0·459–0·899) | 34·5 (3·2–371·2) |
| aβ2GPI IgM | 0·0 (0·0–32·1) | 98·9 (94·2–100·0) | 0·653 (0·451–0·854) | 2·7 (0·1–69·8)* |
| aPS/PT IgG | 54·6 (23·4–83·3) | 93·6 (86·5–97·6) | 0·796 (0·624–0·968) | 17·4 (4·1–73·9) |
| aPS/PT IgM | 45·5 (16·8–76·6) | 94·6 (87·9–98·2) | 0·734 (0·516–0·951) | 14·7 (3·3–65·1) |
*
Logit correction since one of the values in the table was a zero. CI = confidence interval; aPL = anti-phospholipid; LAC = lupus anti-coagulant; aCL = anti-cardiolipin; GPI = glycoprotein I; aPS/PT = anti-phosphatidylserine/prothrombin complex; Ig = immunoglobulin.