Table 3.
Significant Associations Among Pre- and Post Weight Loss Bone Markers and Body Composition, Endocrine and Inflammatory Markers in Fifty-one Women
| Pre Adipo- nectin |
Post Adipo- nectin |
Post HOMA |
Post Ghrelin |
▲ Ghrelin |
Pre IL-1β |
Post IL-1β |
Pre TNF-α |
Post TNF-α |
Pre CRP |
Post Fat % |
▲ Fat % |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre BAP | 0.32 (0.02) | 0.36 (0.01) | ||||||||||
| Post BAP | −0.29 (0.04) | −0.31 (0.02) | −0.29 (0.04) | −0.29 (0.04) | 0.41 (0.003) | |||||||
| ▲ BAP | ||||||||||||
| Pre OC | 0.37 (0.01) | |||||||||||
| Post OC | 0.28 (0.04) | −0.30 (0.03) | ||||||||||
| ▲ OC | −0.33 (0.02) | −0.33 (0.02) | ||||||||||
| Post CTX | −0.28 (0.04) | |||||||||||
| ▲ CTX | −0.34 (0.01) | |||||||||||
| Pre PYD | ||||||||||||
| Post PYD | 0.33 (0.02) | |||||||||||
| ▲ PYD | −0.29 (0.04) | |||||||||||
| Pre GLP-1 | −0.29 (0.04) |
Values are Pearson correlations (r) with (p values) below. Pre- = prior to weight loss; Post-after weight loss; ▲= change; BAP = bone alkaline phosphatase; CTX = carboxy-terminal collagen crosslinks; PYD = pyridinoline crosslinks; OC = osteocalcin; IL= interleukin; TNF-α = tumor necrosis factor- alpha; CRP = c-reactive protein; GLP-1 = glucagon like peptide-1.