Table 3.
Validating expression of gene-coded secreted proteins changes in microarrays and qPCR
| Gene symbol | Gene name | Fold change | |
|---|---|---|---|
| Microarray# | qPCR | ||
| Lipi | Lipase, member I | 4.6 | 8.3* |
| Figf | c-fos induced growth factor | 2.1 | 15.7* |
| Slpi | Secretory leukocyte peptidase inhibitor | 1.8 | 7.0* |
| Rbp4 | Retinol binding protein 4, plasma | 1.7 | 1.7* |
| Ecm1 | Extracellular matrix protein 1 | 1.6 | 2.0 |
| Mfge8 | Milk fat globule-EGF factor 8 protein | 1.5 | 8.1* |
| Chad | Chondroadherin | 0.7 | 0.3* |
| Comp | Cartilage oligomeric matrix protein | 0.7 | 0.6 |
| Fgf9 | Fibroblast growth factor 9 | 0.6 | 0.8* |
| Thbd | Thrombomodulin | 0.6 | 0.06* |
| Car2 | Carbonic anhydrase 2 | 0.6 | 0.3* |
| Srgn | Serglycin | 0.5 | 0.5 |
| Ostn | Osteocrin | 0.3 | 0.05* |
The values in microarray and qPCR analysis are presented as fold changes between three Rs1 and three control mice.
P<0.01 in microarray and
P≤0.05 in qPCR