Skip to main content
. Author manuscript; available in PMC: 2016 Jun 4.
Published in final edited form as: Neuroscience. 2015 Mar 27;295:126–138. doi: 10.1016/j.neuroscience.2015.03.051

Figure 3. Acoustic Disturbance Provides Susceptibility to Anxiety-like Behavior in Mice with TIC Injury in the Elevated Plus Maze.

Figure 3

No anxiety-like behaviors were observed in any of the groups tested in the plus maze in a quiet environment (NS). After acoustic startle (ST), testing separate groups determined mice with TIC injury spent significantly more time in the open arms (A) compared to sham or non-startled mice with TIC injury. Mice with TIC injury had significantly more transitions into the open arms as compared to the non-startled mice with TIC injury or sham group (B). Head dips into the open arms were significantly increased in the sham group after startle, but were not significantly different in other groups (C). n= 7–8, Comparison of non-startle (NS) vs startle (ST) group means for each conditions with t- test ***p<0.001, **p<0.01,*p<0.05.