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. 2015 Mar 2;125(17):2597–2604. doi: 10.1182/blood-2014-12-615948

Table 1.

Molecular outcomes from treatment of HSPCs with ZFNs and an oligonucleotide donor

Outcome Frequency (%)
No change 46.1
NHEJ-mediated deletions 30.5
Oligonucleotide-templated gene modification 18.8
NHEJ-mediated insertions 2.8
Half gene modification, half NHEJ 1.5
Capture of the donor oligonucleotide 0.4