Table 2.
Mean and standard deviations (SD) for the cognitive assessments, with p values shown for the main effect of time (pre and post dose) and the time × treatment interaction
| SUCCAB task | Treatment group | Number | Baseline mean (SD) | Post dose mean (SD) | Time p | Interaction p |
|---|---|---|---|---|---|---|
| Simple reaction rt | Multivitamin | 37 | 320 (107) | 332 (104) | 0.94 | 0.38 |
| Placebo | 36 | 311 (82) | 301 (35) | |||
| Stroop congruent rt | Multivitamin | 39 | 795 (114) | 759 (124) | <0.001*** | 0.97 |
| Placebo | 37 | 766 (109) | 731 (102) | |||
| Stroop incongruent rt | Multivitamin | 37 | 898 (131) | 909 (146) | 0.29 | 0.99 |
| Placebo | 35 | 877 (108) | 889 (123) | |||
| Stroop interference rt | Multivitamin | 37 | 104 (69) | 152 (82) | <0.001*** | 0.40 |
| Placebo | 34 | 118 (100) | 149 (89) | |||
| Contextual recognition rt | Multivitamin | 35 | 1019 (97) | 1022 (94) | 0.39 | 0.58 |
| Placebo | 36 | 995 (106) | 1013 (121) | |||
| Contextual recognition % | Multivitamin | 35 | 79.3 (14.1) | 81.6 (12.1) | 0.23 | 0.98 |
| Placebo | 35 | 77.1 (15.1) | 79.4 (13.1) | |||
| Immediate recognition rt | Multivitamin | 39 | 1015 (111) | 1014 (115) | 0.04* | 0.06 |
| Placebo | 35 | 1036 (136) | 990 (112) | |||
| Immediate recognition % | Multivitamin | 39 | 71.0 (12.9) | 76.7 (11.0) | <0.001*** | 0.71 |
| Placebo | 35 | 70.8 (12.1) | 77.6 (12.1) | |||
| Delayed recognition rt | Multivitamin | 37 | 1017 (86) | 1009 (114) | 0.24 | 0.64 |
| Placebo | 36 | 1000 (88) | 982 (106) | |||
| Delayed recognition % | Multivitamin | 37 | 69.4 (14.3) | 73.6 (12.4) | 0.01* | 0.56 |
| Placebo | 36 | 70.5 (10.6) | 73.0 (12.4) | |||
| Working memory rt | Multivitamin | 39 | 1056 (147) | 1020 (154) | 0.03* | 0.70 |
| Placebo | 36 | 1029 (131) | 994 (125) | |||
| Working memory % | Multivitamin | 39 | 69.8 (15.0) | 72.8 (14.3) | 0.01** | 0.58 |
| Placebo | 37 | 67.3 (15.6) | 72.0 (13.0) |
*p < 0.05 level, **p < 0.01 level, ***p < 0.001 level