Table 1.
Characteristics of studies eligible in the meta-analysis
| Author | Year | Type of tumor | Numbers | Genotype(case/control) | MAF (%) | P(HWE) | |||
|---|---|---|---|---|---|---|---|---|---|
| case | control | *1/1 | *1/2 | *2/2 | |||||
| Deng et al. (2005) | 2005 | Lung cancer | 166 | 134 | 54/67 | 91/59 | 21/8 | 75(28.0) | 0.2850 |
| Li et al. (2006) | 2006 | Lung cancer | 131 | 104 | 70/57 | 56/36 | 5/11 | 58(27.9) | 0.1554 |
| Liu et al. (2007) | 2007 | Gastric cancer | 214 | 350 | 88/199 | 107/133 | 19/18 | 169(24.1) | 0.4835 |
| Sun et al. (2007) | 2007 | lymphoma | 166 | 350 | 72/199 | 71/133 | 23/18 | 169(24.1) | 0.4835 |
| Cheng et al. (2008) | 2008 | Colon cancer | 253 | 350 | 113/199 | 112/133 | 28/18 | 169(24.1) | 0.4835 |
| Rectal cancer | 237 | 350 | 126/199 | 101/133 | 10/18 | 169(24.1) | 0.4835 | ||
| esophageal cancer | 211 | 350 | 123/199 | 80/133 | 8/18 | 169(24.1) | 0.4835 | ||
| Sun et al. (2008) | 2008 | hepatocellular | 190 | 175 | 72/99 | 110/67 | 8/9 | 85(24.3) | 0.587 |
| Wang and Zhang (2010) | 2010 | Pancreatic cancer | 58 | 156 | 24/74 | 26/67 | 8/15 | 97(31.1) | 0.9766 |
| Qi (2010) | 2010 | liver | 86 | 77 | 27/36 | 51/34 | 8/7 | 48(31.2) | 0.7985 |
| Meng et al. (2011) | 2011 | Cervical cancer | 317 | 416 | 127/225 | 153/163 | 37/28 | 219(26.3) | 0.8352 |
| Fan et al. (2012) | 2012 | breast | 732 | 649 | 326/346 | 342/262 | 64/41 | 344(26.5) | 0.3556 |
| Li et al. (2012) | 2012 | breast | 208 | 211 | 90/129 | 100/76 | 18/6 | 88(20.9) | 0.1853 |
| Yang et al. (2012) | 2012 | Gallbladder cancer | 91 | 155 | 34/88 | 45/57 | 12/10 | 77(24.8) | 0.8508 |
| Wang et al. (2012) | 2012 | liver | 303 | 515 | 107/272 | 156/205 | 40/38 | 281(27.3) | 0.9415 |
| Zhai et al. (2012) | 2012 | hepatocellular | 102 | 135 | 37/ | 52/ | 13/ | (24.07) | - |
| Xu et al. (2012) | 2012 | ovarian | 282 | 365 | 122/231 | 115/108 | 45/26 | 160(21.9) | 0.64 |
| Meng et al. (2013) | 2013 | Endometrial cancer | 283 | 378 | 93/200 | 135/140 | 55/38 | 216(28.6) | 0.0718 |
| Wang et al. (2013) | 2013 | nasopharyngeal cancer | 134 | 327 | 74/163 | 48/145 | 12/19 | 183(28.0) | 0.0700 |
| Tang et al. (2014) | 2014 | NSCLC | 392 | 437 | 158/226 | 171/176 | 63/35 | 246(28.1) | 0.9284 |
*MAF, minor allele frequency, in this study, minor allele refers to allele*2, P (HWE), P value for test of Hardy-Weinberg equilibrium.