Table 3.
The spectrum of causative pathogens isolated from late infected pancreatic necrosis
| Case no. | Isolated pathogen from IPN | Characteristics of the pathogen | Antibiotic susceptibility of the pathogen |
|---|---|---|---|
| 1 | Staphylococcus aureus | G+, facultative anaerobic, skin commensal, oral commensal (±) | Methicillin-sensitive |
| Fusobacterium nucleatum | G−, anaerobic, oral commensal | Amoxicillin, clindamycin, metronidazole | |
| 2 | Propionibacterium acnes | G+, anaerobic, oral commensal | Amoxicillin, clindamycin |
| 3 | Actinomyces naeslundii | G+, anaerobic, oral commensal | Amoxicillin, clindamycin |
| 4 | Escherichia coli | G−, facultative anaerobic, enteric bacillus | Ampicillin, ciprofloxacin, gentamicin, cephazolin |
| Bacteroides fragilis | G−, anaerobic, enteric bacillus | Amoxicillin/clavulanate, clindamycin, metronidazole | |
| Peptostreptococcus spp. | G+, anaerobic, oral, skin and GI commensal | Penicillin, clindamycin, metronidazole | |
| 5 | Streptococcus intermedius | G+, microaerobic, oral commensal | Amoxicillin, clindamycin |
| 6 | Negative | – | – |
| 7 | Prevotella melaninogenica | G−, anaerobic, oral commensal | Amoxicillin/clavulanate, metronidazole (amoxicillin, clindamycin–resistant) |
| Streptococcus constellatus | G+, microaerobic, oral commensal | Amoxicillin, clindamycin, erythromycin |
IPN infected pancreatic necrosis, G gram staining, GI gastrointestinal