Table 2.
Temporal lobe epilepsy patient clinical and pathological details
| Identifier | Gender | Age (y) | Tissue diagnosis and pathology | Antiepileptic drugs | RIN | Analyses |
|---|---|---|---|---|---|---|
| WG1_1 | M | 59 | R side; HS grade 1. Gliosis only; No GCD/MFS | Ph, Clon, Zon | 5.9 | GM, Gexp, miRexp, miRM |
| WG1_2 | F | 31 | R side, HS grade 1. Gliosis only; No GCD/MFS | Clon, Lev, Ox | 8.6 | GM, Gexp, miRexp, miRM |
| WG1_3 | F | 16 | R side, HS grade 1. Mild astrogliosis; No GCD/MFS | Ox, Zon | 5.5 | GM, Gexp, miRexp |
| WG1_4 | M | 46 | L side, HS grade 1. Mild-moderate astrogliosis; No GCD/MFS | Lev, Ph | 4.1 | GM, Gexp, miRexp, miRM |
| WG1_5 | M | 39 | R side, HS grade 1. Gliosis only; No MFS/GCD | Lam, Lev | 8.5 | GM, Gexp, miRexp, miRM |
| WG4_1 | M | 57 | L side, HS grade 4. Mild GCD | Car, Lam | 9.0 | GM, Gexp, miRexp, miRM |
| WG4_2 | M | 37 | L side, HS grade 4. GCD, MFS | Car, Lev | 8.8 | GM, Gexp, miRexp, miRM |
| WG4_3 | M | 40 | R side, HS grade 4. GCD, MFS | Car, Dz | 6.9 | GM, Gexp, miRexp |
| WG4_4 | M | 52 | R side, HS grade 4. Weak MFS, No GCD | Car | 4.8 | GM, Gexp, miRexp, miRM |
Car = carbamazepine; Clon = clonazepam; Dz = diazepam; GM = gene promoter methylation analysis; GCD = granule cell dispersion; Gexp = gene expression analysis; HS = hippocampal sclerosis; L = left side resection; Lam = lamotrigine; Lev = levetiracetam; MFS = mossy fibre sprouting (dynorphin staining); miRexp = microRNA expression analysis; miRM = microRNA methylation analysis; Ox = oxcarbazapine; Ph = phenytoin; R = right side resection; RIN = RNA integrity number; Zon = zonisamide.