Table 1.
Ref. | No. of cases (control group/treatment group) | Bevacizumab treatment regimen | Modified Jadad score |
Kabbinavar et al[9] | 104 (36/68) | 5 mg/kg or 10 mg/kg every 14 d | 4 |
Kabbinavar et al[10] | 209 (105/104) | 5 mg/kg every 14 d | 5 |
Tebbutt et al[11] | 312 (156/156) | 7.5 mg/kg every 21 d | 4 |
Stathopoulos et al[6] | 224 (108/114) | 7.5 mg/kg every 21 d | 4 |
Saltz et al[7] | 1400 (701/699) | 5 mg/kg every 14 dor 7.5 mg/kg every 21 d | 6 |
Hurwitz et al[12] | 813 (411/402) | 5 mg/kg every 21 d | 4 |
Giantonio et al[8] | 577 (291/286) | 10 mg/kg every 14 d | 3 |
Guan et al[13] | 214 (72/142) | 5 mg/kg every 14 d | 4 |
de Gramont et al[14] | 2306 (1151/1155) | 5 mg/kg every 14 d | 4 |
Bennouna et al[15] | 820 (411/409) | 5 mg/kg every 14 d or 7.5 mg/kg every 14 d | 5 |