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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2014 Apr 29;278(2):107–115. doi: 10.1016/j.taap.2014.04.016

Fig. 4.

Fig. 4

Comparative effects of DON congeners on IL-1β mRNA expression. Mice were orally gavaged with 8-ketotrichothecenes (A,B) and D3G, EN139528, EN139544 (C,D) at 2.5 mg/kg bw and then spleens removed at 2 h (A,C) or 6 h (B,D) post administration IL-1β mRNA expression was determined by real-time PCR. Data are mean ± SEM (n=6/gp) of mRNA fold change relative to vehicle control and were analyzed as described in Fig. 4 legend