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Seddon and Sunderland Classification of Nerve Injury
| Seddon | Sunderland | Injury |
|---|---|---|
| Neurapraxia | Grade I | Focal segmental demyelination |
| Axonotmesis | Grade II | Axon damaged with intact endoneurium |
| Axonotmesis | Grade III | Axon and endoneurium damaged with intact perineurium |
| Axonotmesis | Grade IV | Axon, endoneurium, and perineurium damaged with intact epineurium |
| Neurotmesis | Grade V | Complete nerve transection. |
| Grade VI (MacKinnon & Dellon) | Mixed levels of injury along the nerve |
