Table 3.
Complementary analyses: Medical resource utilization and prescribed medications in 2008 in the 3 subgroups identified within the high-ICS-ratio group
| 50% ≤ R < 60% | 60% ≤ R < 90% | 90% ≤ R | p-value | |
|---|---|---|---|---|
| UK | ||||
| Number of patients | 10,929 | 3,715 | 2,094 | |
| Number of respiratory medication prescriptions (mean) | 7.5 | 6.86 | 3.62 | <0.0001 |
| Systemic corticosteroids | ||||
| Patients with ≥ 1 prescription (%) | 12.7% | 14.7% | 8.9% | <0.0001 |
| Number of prescriptions (mean) | 0.2 | 0.24 | 0.16 | 0.0006 |
| Antibiotics (a) | ||||
| Patients with ≥ 1 prescription (%) | 41.9% | 43.4% | 35.5% | <0.0001 |
| Number of prescriptions (mean) | 0.8 | 0.86 | 0.7 | 0.0001 |
| Patients with ≥ 1 prescription of LABA-ICS fixed combination (%) | 38.9% | 56.2% | 51% | <0.0001 |
| Number of GP visits (mean) | 6.5 | 7.2 | 5.9 | <0.0001 |
| France (b) | ||||
| Number of patients | 783 | 597 | 673 | |
| Number of respiratory medication prescriptions units (mean) | 9.61 | 11 | 5.67 | <0.0001 |
| Systemic corticosteroids | ||||
| Patients with ≥ 1 prescription (%) | 29.9% | 33.3% | 28.7% | 0.178 |
| Number of units (b) (mean) | 0.84 | 0.82 | 0.77 | 0.811 |
| Antibiotics (a) | ||||
| Patients with ≥ 1 prescription (%) | 50.7% | 55.8% | 53.3% | 0.17 |
| Number of units (b) (mean) | 1.61 | 1.91 | 1.52 | 0.0159 |
| Patients with ≥ 1 prescription of LABA-ICS fixed combination (%) | 75.5% | 89.9% | 82% | <0.0001 |
| Number of GP visits (mean) | 5.4 | 5.8 | 5.6 | 0.273 |
(a)Beta-lactams, cephalosporins (first to third generations), macrolides and fluoroquinolones.
(b)Canisters for inhaled therapy and packages for oral therapy.