Table 1.

Relationship of preoperative plasma fibrinogen level with clinicopathological parameter

Variable	N	Fibrinogen level	P value	Fibrinogen level		P value
		Mean ± SD		Normal	Hyperfibrinogenemia
		(g/L)		(1.5 to 4 g/L)	(≥4 g/L)
Gender
Male	95	3.94 ± 0.98	0.034	51	44	0.252
Female	24	3.48 ± 0.73		16	8
Age
<60	59	3.7 ± 0.94	0.101	38	21	0.077
≥60	60	3.99 ± 0.95		29	31
Smoking history
Yes	71	3.91 ± 0.95	0.371	29	19	0.457
No	48	3.75 ± 0.96		38	33
Location
Upper	15	3.56 ± 0.74	0.144	9	6	0.528
Middle	67	3.78 ± 0.99		40	27
Lower	37	4.08 ± 0.93		18	19
Tumor length
<3.85 cm	64	3.56 ± 0.88	<0.001	42	22	0.027
≥3.85 cm	55	4.18 ± 0.93		25	30
Differentiation
Well	33	3.94 ± 0.81	0.782	17	16	0.676
Moderate	51	3.81 ± 1.09		31	20
Poor	35	3.8 ± 0.87		19	16
Tumor stage
T1	18	3.25 ± 0.68	0.001	15	3	0.013
T2	26	3.67 ± 0.91		17	9
T3	67	3.97 ± 0.92		33	34
T4	8	4.69 ± 1.11		2	6
Lymph node status
Negative	75	3.77 ± 0.94	0.267	46	29	0.149
Positive	44	3.97 ± 0.97		21	23
Pathological stages
I	21	3.48 ± 0.81	0.034	15	6	0.011
II	58	3.79 ± 0.98		37	21
III	40	4.12 ± 0.91		15	25
Adjuvant treatment
None	71	3.87 ± 0.95	0.962	37	34	0.307
Radiotherapy	25	3.83 ± 0.97		13	12
Chemotherapy	11	3.9 ± 0.82		8	3
CRT	12	3.72 ± 1.11		9	3
Recurrence
Yes	81	3.94 ± 0.97	0.116	40	41	0.026
No	38	3.65 ± 0.89		27	11

SD, standard deviation; CRT, chemoradiotherapy. P < 0.05 is of significance.