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. Author manuscript; available in PMC: 2015 Apr 24.
Published in final edited form as: Curr Top Microbiol Immunol. 2012;361:93–111. doi: 10.1007/82_2012_219

Fig. 2.

Fig. 2

Proposed model of PMT entry and trafficking. Tfn transferrin, TfnR transferrin receptor, CT cholera toxin, Rab5 GTPase marker of recycling endosomes, TGN trans-Golgi network, ER endoplasmic reticulum, SM/PC sphingomyelin/PC receptors of PMT, Arf6-CA constitutively active Arf6 GTPase, Arf6-DN dominantly negative Arf6, CcD cytochalasin D, LY294002 PI3 K inhibitor of early endosome-recycling endosome fusion, Noc nocodazole, BafA1 bafilomycin A1, Bfa brefeldin A. [Adapted from (Repella et al. 2011)]