Table 2.
Variable | Young Non-exercising
|
Older Non-exercising
|
Older Exercise-Trained
|
|||
---|---|---|---|---|---|---|
Placebo | Salsalate | Placebo | Salsalate | Placebo | Salsalate | |
SBP (mm Hg) | 110 ± 4 | 109 ± 3 | 122 ± 4 | 117 ± 4 | 111 ± 4 | 111 ± 4 |
DBP (mm Hg) | 61 ± 3 | 58 ± 2 | 73 ± 3 * | 71 ± 3 | 69 ± 2 * | 70 ± 2 |
Total cholesterol (mg/dL) | 142 ± 7 | 126 ± 6 * | 182 ± 7 * | 163 ± 5 † | 186 ± 9 * | 167 ± 9 ‡ |
LDL-cholesterol (mg/dL) | 79 ± 7 | 73 ± 5 | 114 ± 5 * | 102 ± 5 † | 113 ± 7 * | 107 ± 8 |
HDL-cholesterol (mg/dL) | 47 ± 3 | 43 ± 3 | 47 ± 3 | 49 ± 3 | 49 ± 4 | 48 ± 3 |
Triglycerides (mg/dL) | 58 ± 2 | 50 ± 4 | 104 ± 13 * | 59 ± 4 † | 106 ± 12 * | 64 ± 6 ‡ |
Glucose (mg/dL) | 87 ± 2 | 83 ± 2 | 89 ± 2 | 84 ± 2 | 86 ± 1 | 82 ± 2 |
C-reactive protein (mg/L) | 0.5 ± 0.1 | 0.7 ± 0.2 | 1.0 ± 0.2 | 1.2 ± 0.2 | 0.6 ± 0.1 | 0.7 ± 0.1 |
Interleukin-6 (pg/mL) | 0.8 ± 0.1 | 1.0 ± 0.2 | 1.4 ± 0.3 | 1.2 ± 0.2 | 0.8 ± 0.1 | 0.6 ± 0.1 |
TNFα (pg/ml) | 0.8 ± 0.1 | 0.8 ± 0.0 | 1.1 ± 0.1 | 1.3 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 |
Data are mean ± SE. SBP, systolic blood pressure; DBP, diastolic blood pressure; TNFα, tumor necrosis factor alpha.
P<0.05 vs. young non-exercising placebo,
P<0.05 vs. older non-exercising placebo,
P<0.05 vs. older trained placebo