Table 2.

Blood pressure and circulating factors during placebo and salsalate

Variable	Young Non-exercising		Older Non-exercising		Older Exercise-Trained
	Placebo	Salsalate	Placebo	Salsalate	Placebo	Salsalate
SBP (mm Hg)	110 ± 4	109 ± 3	122 ± 4	117 ± 4	111 ± 4	111 ± 4
DBP (mm Hg)	61 ± 3	58 ± 2	73 ± 3 *	71 ± 3	69 ± 2 *	70 ± 2
Total cholesterol (mg/dL)	142 ± 7	126 ± 6 *	182 ± 7 *	163 ± 5 †	186 ± 9 *	167 ± 9 ‡
LDL-cholesterol (mg/dL)	79 ± 7	73 ± 5	114 ± 5 *	102 ± 5 †	113 ± 7 *	107 ± 8
HDL-cholesterol (mg/dL)	47 ± 3	43 ± 3	47 ± 3	49 ± 3	49 ± 4	48 ± 3
Triglycerides (mg/dL)	58 ± 2	50 ± 4	104 ± 13 *	59 ± 4 †	106 ± 12 *	64 ± 6 ‡
Glucose (mg/dL)	87 ± 2	83 ± 2	89 ± 2	84 ± 2	86 ± 1	82 ± 2
C-reactive protein (mg/L)	0.5 ± 0.1	0.7 ± 0.2	1.0 ± 0.2	1.2 ± 0.2	0.6 ± 0.1	0.7 ± 0.1
Interleukin-6 (pg/mL)	0.8 ± 0.1	1.0 ± 0.2	1.4 ± 0.3	1.2 ± 0.2	0.8 ± 0.1	0.6 ± 0.1
TNFα (pg/ml)	0.8 ± 0.1	0.8 ± 0.0	1.1 ± 0.1	1.3 ± 0.1	1.0 ± 0.1	1.0 ± 0.1

Data are mean ± SE. SBP, systolic blood pressure; DBP, diastolic blood pressure; TNFα, tumor necrosis factor alpha.

^*P<0.05 vs. young non-exercising placebo,

^†P<0.05 vs. older non-exercising placebo,

^‡P<0.05 vs. older trained placebo