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. 2015 May;21(5):923–934. doi: 10.1261/rna.048421.114

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© 2015 Burke et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 8. — Proposed U6 recycling pathway from post-catalytic spliceosomes for wild-type (top) and U4–G41U/U6–A62G,A91G triple mutant (bottom) cells. Asterisks indicate mutations. Dashed line indicates a reduced forward equilibrium constant that results in an increased accumulation of U2/U6** snRNP. The Lsm2-8 proteins (not shown) likely act in concert with Prp24.