Table 1.

Main estrategies to optimize the erythrocyte mass and coagulation status.

Research study	Main estrategies to optimize the erythrocyte mass and coagulation
Drews[17]	To identify anemia, thrombocytopenia and coagulopathy
Goodnough[18]	To treat iron deficiencies
Weltert et al.[20]	r-Hu-EPO in the preoperative period for anemic patients
Corwin et al.[21]	Dose of 40,000 UI/week reduces blood transfusions
Silverberg et al.[24]	Anabolic androgenic therapy can optimize the responses to r-Hu-EPO
Bussel et al.[29]	Eltrombopag stimulates trombocytopoiesis and reduces platelets transfusion
Wang et al.[30]	r-Hu-TPO stimulates trombocytopoiesis and reduces platelets transfusion

r-Hu-EPO=Recombinant human erythropoietin, r-Hu-TPO=Recombinant human thrombopoietin