Skip to main content
. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Biol Blood Marrow Transplant. 2014 Nov 1;21(2):281–287. doi: 10.1016/j.bbmt.2014.10.024

Table 2.

Univariate analysis of progression-free survival between subgroups of patients with persistent indolent B-cell malignancies undergoing nonmyeloablative allogeneic transplantation.

N Median PFS
(months)
3-Year PFS HR (95% CI) P
No RIT 71 19.0 44% 1.0
RIT 18 53.0 56% 0.7 (0.4–1.5) 0.36
Disease Bulk ≤5 cm 67 30.8 49% 1.0
Disease Bulk >5 cm 22 14.8 36% 1.5 (0.9–2.7) 0.15
Other Histologies 27 18.1 37% 1.0
CLL/SLL 62 23.8 50% 0.8 (0.5–1.5) 0.56
Related Donor 47 37.6 53% 1.0
Unrelated Donor 42 19.0 38% 1.1 (0.7–1.8) 0.76
Non-High-Risk Cytogeneticsa 33 53.0 61% 1.0
High-Risk Cytogeneticsa 14 19.9 43% 1.2 (0.5–2.8) 0.63

PFS, progression-free survival; HR, hazard ratio; CI, confidence interval; RIT, radioimmunotherapy; CLL/SLL, chronic lymphocytic leukemia/small lymphocytic lymphoma; MRD, matched related donor;.

a

“High-risk cytogenetics” were those patients with CLL/SLL that harbored deletion 11q and/or deletion 17p; all others with CLL/SLL from whom cytogenetic data were available were considered “non-high-risk”.