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MNV infection at early stages of atherosclerosis development does not alter lesion size. (A) The size of the aortic sinus lesion was determined from Movat-pentachrome–stained serial sections of hearts of Ldlr−/− mice fed an atherogenic diet and treated with either MNV or vehicle only (clarified RAW264.7 cell lysate). (B) Macrophage infiltration was assessed by using antiMac2 antibody and is expressed as percentage of lesion area. Bars represent means ± SEM.
