Table 1.
Demographic and Health Characteristics of the Cohort at Midlife and Late Life (n = 3,864), AGES-Reykjavik Study, 1967–2006
| Characteristic | Weight Categorya |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Normal Weight (n = 2,046) |
Overweight (n = 1,504) |
Obese (n = 314) |
|||||||
| Mean (SD) | No. | % | Mean (SD) | No. | % | Mean (SD) | No. | % | |
| No. of follow-up years | 26.5 (4.7) | 26.2 (4.9) | 24.8 (5.2) | ||||||
| APOE ε4 allele carriers | 595 | 29.1 | 423 | 28.1 | 77 | 24.5 | |||
| Educational level | |||||||||
| Primary school | 461 | 22.5 | 341 | 22.7 | 88 | 28.0 | |||
| Secondary school | 996 | 48.7 | 767 | 51.0 | 161 | 51.3 | |||
| College | 351 | 17.2 | 222 | 14.8 | 38 | 12.1 | |||
| University | 238 | 11.6 | 174 | 11.6 | 27 | 8.6 | |||
| Midlife measures | |||||||||
| Age, years | 49.4 (4.8) | 50.1 (4.7) | 51 (4.4) | ||||||
| Physically activeb | 428 | 20.9 | 285 | 19.0 | 55 | 17.5 | |||
| Systolic BP, mm Hg | 128.4 (15.4) | 134.5 (16.3) | 140.1 (19.2) | ||||||
| Diastolic BP, mm Hg | 81.2 (8.8) | 85.6 (9.4) | 87.8 (10.8) | ||||||
| Cholesterol, mg/dL | 242.4 (42.3) | 247.6 (43.2) | 243.2 (39.4) | ||||||
| Late-life measures | |||||||||
| Age, years | 75.9 (5.2) | 76.3 (5.2) | 75.8 (4.9) | ||||||
| Prevalent CHD | 358 | 17.5 | 380 | 25.3 | 66 | 21.0 | |||
| Type 2 diabetes | 132 | 6.5 | 225 | 15.0 | 75 | 23.9 | |||
| CAC, Agatston units | 0.6 | 0.9 | 0.8 | 1.2 | 0.9 | 1.4 | |||
| Hypertension | 1555 | 76.0 | 1263 | 84.0 | 278 | 88.5 | |||
| Cholesterol, mg/dL | 222.2 (44.6) | 212.3 (44.5) | 208.3 (41.6) | ||||||
| Depression | 145 | 7.1 | 99 | 6.6 | 22 | 7.0 | |||
| Smoking status | |||||||||
| Never smoker | 855 | 41.8 | 633 | 42.1 | 151 | 48.1 | |||
| Former smoker | 910 | 44.5 | 727 | 48.3 | 128 | 40.8 | |||
| Current smoker | 281 | 13.7 | 144 | 9.6 | 35 | 11.2 | |||
| Drinking status | |||||||||
| Abstainer | 413 | 20.2 | 339 | 22.5 | 95 | 30.3 | |||
| Former drinker | 223 | 10.9 | 199 | 13.2 | 39 | 12.4 | |||
| Current drinker | 1410 | 68.9 | 966 | 64.2 | 180 | 57.3 | |||
Abbreviations: APOE, apolipoprotein E; BP, blood pressure; CAC, coronary artery calcium; CHD, coronary heart disease; SD, standard deviation.
a Normal weight was defined as a body mass index (measured as weight in kilograms divided by height in meters squared) of 18.5–24.9; overweight was defined as a body mass index of 25–29.9; and obese was defined as a body mass index ≥30.
b Physically active subjects were those who reported 5 hours or more of exercise per week.