Table 1. DAVID gene enrichment scores of functional category keywords. In total, 541 DEGs were analyzed against Uniprot functional categories and enriched gene lists were generated for each functional category.

Functional Categories (Uniprot)	Enrichment Score of Cluster	Gene Count	Genes
SP_PIR_KEYWORDS: disulfide bond	3.810	83	A2M, MICB, NRTN, GABRB1, EDN1, JAG1, DLK1, CXCL10, SLC7A7, UNC5B, GSN, HAMP, CNTNAP2, PLA1A, CYGB, LOXL4, FABP5L2, CFD, CEACAM1, KNG1, MATN3, STC2, ICAM2, LYZ, OLFML2A, TNFRSF14, HEPACAM2, HLA-E, SIRPA, MMP11, AADAC, INHBE, IGF2R, ULBP1, LRP11, ULBP2, TFPI, ROR1, VCAN, PRNP, CTSH, LUM, KITLG, CXCL6, LEAP2, AHSG, COL9A2, NPTX2, FGB, TFF2, TFF3, THBS1, ANGPTL2, GCNT1, CD7, ANGPTL4, HPN, GLRB, LGALS3, EFEMP1, CELSR2, FZD2, C4BPA, COL4A6, FZD7, COL4A5, NOTCH3, DNASE2, DKK1, COL14A1, GPR37, PTP4A3, PI3, LASS1, C1RL, EPOR, ADM2, GDF15, FABP5, IGFBP4, PON3, CD14, HABP2, VLDLR
SP_PIR_KEYWORDS: hydroxylation	2.521	8	KNG1, COL9A2, COL14A1, COL1A2, CELSR2, COL2A1, COL4A6, COL4A5
SP_PIR_KEYWORDS: methylation	2.339	18	FUS, HIST1H2AC, HIST2H2AA3, HIST2H2AA4, HIST1H2BD, HIST1H1C, EEF1A2, RHOQ, HIST2H4A, RPL29, RND2, HIST1H2BK, TAF15, HIST2H2BE, PPP2CA, HIST2H2AC, LOC399942, THOC4, RASD1, HIST1H4H
SP_PIR_KEYWORDS: lyase	2.261	11	DDC, CTH, ENO2, ACMSD, HAL, GUCY1A3, ENO3, CA2, GUCY2C, PCK2, GAD1
SP_PIR_KEYWORDS: microsome	1.912	8	AADAC, UGT2B17, CYP1A1, UGT2B11, HSD17B6, CYP26A1, UGT2B4, UGT2B7