Table 1.
Demographics, Clinical, and Conventional MRI Characteristics
| Multiple Sclerosis | Normal Controls | |
|---|---|---|
| (N = 61) | (N = 30) | |
| Women | N = 42 (69%) | N = 21 (70%) |
| Age (years) | 41.0 ± 8.6 (21-55) | 43.9 ± 6.3 (30-53) |
| Disease duration (years) | 8.3 ± 7.2 (0.2-29.0) | - |
| EDSS score | 1.6 ± 1.7 (0-8.0) | - |
| Timed 25 foot walk | 4.8 ± 4.5 (2.9-38.5) | - |
| T2 (FLAIR) hyperintense lesion volume (ml) | 13.6 ± 11.4 (2.6-49.3) | .44 ± 0.57 (0-2.76) |
| T1 (MDEFT) hypointense cerebral lesion volume (ml) | 6.4 ± 7.4 (0.5-34.0) | .19 ± 0.30 (0-1.28) |
| Disease course—number (%) | ||
| Clinically isolated syndrome | N = 4 (6.6%) | - |
| Relapsing remitting | N = 51 (83.6%) | - |
| Secondary progressive | N = 5 (8.2%) | - |
| Primary progressive | N = 1 (1.6%) | - |
| Receiving disease-modifying therapy | N = 49 (80.3%) | - |
Values in table are: mean ± standard deviation (range); number of subjects (percentage).
EDSS = expanded disability status scale; FLAIR = fluid-attenuated inversion-recovery; MDEFFT = modified driven-equilibrium Fourier transform.