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. 2015 Apr 24;10(4):e0123373. doi: 10.1371/journal.pone.0123373

Table 3. The infants developments between clozapine and other atypical antipsychotic groups a .

Variables Clozapine group (n = 33) Other atypical antipsychotics group (n = 30) Test statistics P value
 Birth weight, kg 3.2 (0.7) 3.3 (0.6) 0.831 0.409
 Low birth weight, n (%) 3 (9.0) 5 (16.7) 0.814 0.367
 Birth height, cm 51.2 (0.8) 50.8 (1.1) 1.312 0.195
 Apgar Scoring at 1 minute 8.6 (0.5) 8.3 (0.6) 2.222 0.030
 Apgar Scoring at 5 minute 9.6 (0.5) 9.4 (0.5) 1.370 0.176
2 months of age
 Weight, kg 5.3 (0.7) 5.0 (0.6) 1.750 0.085
 Height, cm 59.1 (1.1) 58.6 (1.4) 1.565 0.123
 Cognitive scale 89.8 (5.1) 90.6 (7.7) 0.438 0.663
 Language scale 93.4 (6.7) 94.8 (8.3) 0.743 0.460
 Motor scale 90.8 (5.9) 90.0 (5.3) 0.542 0.590
 Social-emotional scale 95.7 (10.0) 95.0 (9.1) 0.288 0.774
 Adaptive behavior scale 89.1 (8.9) 96.3 (7.6) 3.419 0.001
6 months of age
 Weight, kg 8.0 (0.9) 7.9 (0.5) 0.165 0.869
 Height, cm 67.5 (2.2) 67.3 (2.3) 0.382 0.704
 Cognitive scale 98.2 (8.0) 98.7 (9.3) 0.209 0.835
 Language scale 95.0 (5.3) 95.8 (8.2) 0.446 0.657
 Motor scale 99.5 (7.9) 102.2 (9.3) 1.248 0.217
 Social-emotional scale 100.2 (10.1) 99.0 (10.3) 0.472 0.638
 Adaptive behavior scale 94.8 (9.9) 100.5 (6.8) 2.613 0.011
12 months of age
 Weight, kg 10.0 (0.8) 10.1 (0.6) 0.241 0.810
 Height, cm 74.8 (2.2) 75.5 (2.6) 1.125 0.265
 Cognitive scale 100.7 (8.5) 100.2 (7.3) 0.295 0.769
 Language scale 97.4 (6.3) 96.4 (6.5) 0.616 0.540
 Motor scale 101.7 (8.1) 100.9 (7.9) 0.380 0.705
 Social-emotional scale 102.0 (8.5) 102.1 (10.9) 0.027 0.979
 Adaptive behavior scale 98.3 (9.4) 96.3 (7.6) 0.372 0.712

aData are expressed as mean (SD).