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. 2015 Mar 9;290(17):10729–10740. doi: 10.1074/jbc.M115.648410

FIGURE 5.

FIGURE 5.

Residues involved in binding with unfractionated heparin. a, extent of oxidation of Robo1 alone (black bars) compared with heparin-bound Robo1 (gray bars) at the residue level. Error bars, S.D. from a triplicate set of experiments. b, structure highlighting Phe129-Leu130-Arg131 are shown in yellow. An asterisk indicates the residue involved in a heparin dp8 binding reported previously (21).