TABLE 3.
Summary of kinetic data of Robo1-heparin interactions
The data in parentheses are the S.D. values from global fitting of five different concentration injections.
Interaction | ka | kd | KD |
---|---|---|---|
m−1 s−1 | s−1 | m | |
Robo1 WT/heparin | 2.8 × 103 (±2.9 × 102) | 8.6 × 10−4 (±5.1 ×10−5) | 3.1 × 10−7 |
Robo1 Mutant I/heparin | 31 (±2) | 3.4 × 10−4 (±3 ×10−5) | 1.1 × 10−5 |
Robo1 Mutant II/heparin | 44 (±1.4) | 3.4 × 10−4 (±1.5 × 10−5) | 7.8 × 10−6 |